Carbetocin Compared To Oxytocin During Cesarean Delivery

As both oxytocin and carbetocin are used daily in obstetric units all over the world, the investigators find it compelling to investigate whether the hemodynamic and myocardial effects of oxytocin and carbetocin are comparable in healthy women during delivery and determine any potential harmful effects following the use of oxytocin or Carbetocin as uterotonic. Other endpoints relating to uterus tone, blood loss, blood pressure, heart rate, post-operative pain and side effects will also be assessed.

Inclusion Criteria:Normal singleton pregnancy at gestational age of 36 weeks or more.Women with common comorbid diagnoses (diabetes, hypothyroidism, hypertension)pregnancy after in vitro fertilizationExclusion Criteria:placenta praevia or invasive placenta.pre-eclampsia.Bleeding disorder, such as von Willebrand disease type I.Current treatment with low-molecular-weight heparin or other anticoagulation medication (not including aspirin).Any known intolerance to either of the study drugs.Prolonged QT-time.Other serious cardiac disease.Liver or kidney failure.