Association Between PM2.5 Exposure and Ferroptosis in Seizures Patients

This cohort study aims to discover the possible effects of PM2.5 exposures on the Nrf2- dependent ferroptosis pathway in seizure patients. This observational cohort's main question is whether PM2.5 exposures will affect the Nrf2- dependent ferroptosis pathway in seizure patients.Participants will be divided into two groups: the control group and the air pollution to detect the biomarkers of the Nrf2- dependent ferroptosis pathway in seizure patients

Inclusion Criteria:Recently diagnosed with epilepsy (< 2 months)living in this city for more than two yearsno exposure to any chemistry pollution beforeExclusion Criteria:abnormal IL-6 level before starting this pilot cohortother neurological disorders except for epilepsy;endocrine diseases;cancerreceive anti-proinflammatory cytokines therapy