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Active Not Recruiting
NCT05841524
Vector Velocity Imaging in AAA Patients
Conditions: Abdominal Aneurysm, Thrombus
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 14
Sponsor: St. Olavs Hospital
Location: St. Olavs hospital, Trondheim University Hospital Trondheim Trøndelag
Summary
The goal of this observational study is to perform an in vivo feasibility study using real time (3D) ultrasound based vector flow imaging in 10 AAA patients (5 with intraluminal thrombus and 5 without intraluminal thrombus). Furthermore, the investigators will investigate the added value of contrast microbubbles in these high framerate, plane wave ultrasound measurements.
Included patients will undergo ultrasound scanning of their AAA, using multiple ultrasound sequences. Sequences will be tested with and without the addition of ultrasound contrast microbubbles.
Eligibility Criteria
Inclusion Criteria:
* Diagnosed with AAA
* AAA diameter below treatment threshold of 5.5 cm
Exclusion Criteria:
* Hypersensitivity to the active substance(s) or any of the excipients in Sonovue
* Right-to-left cardiac shunt
* Severe pulmonary hypertension (pulmonary artery pressure \> 90mmHg)
* Uncontrolled systemic hypertension
* Severe pulmonary disease (e.g. COPD GOLD 3 or 4, adult respiratory distress syndrome)
* Clinically unstable cardiac disease (recent, \< 3 months, or ongoing myocardial infarction, unstable angina at rest, recent percutaneous coronary intervention, clinically worsening cardiac symptoms, severe cardiac arrhythmia's, endocarditis, etc.)
* Prosthetic valves
* Loss of renal function (GFR \< 31 ml/min), end-stage renal disease
* End-stage liver disease
* Sepsis
Source: ClinicalTrials.gov (NCT05841524). StuddyBuddy aggregates publicly available trial information.