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Completed
NCT05907668
A Proof-of-Concept Study to Assess Batoclimab in Participants With Graves' Disease
Conditions: Graves Disease
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE2
Enrollment: 32
Sponsor: Immunovant Sciences GmbH
Location: Site Number - 6505 Mainz
Summary
The purpose of this study is to assess the efficacy and safety of 24 weeks of treatment with batoclimab in adult participants with biochemically documented hyperthyroidism due to GD who have failed to achieve euthyroidism on antithyroid drugs (ATDs).
Eligibility Criteria
Inclusion Criteria:
* Have serologically confirmed GD as documented by presence of elevated stimulatory thyrotropin receptor antibody (TSH-R-Ab) level (i.e., \> specimen-to-reference ratio of 140%) at the Screening Visit.
* Have active hyperthyroidism due to GD with the following laboratory values at the Screening Visit:
* TSH \< LLN
* FT3 \> upper limit of normal (ULN) and \ ULN and \
Source: ClinicalTrials.gov (NCT05907668). StuddyBuddy aggregates publicly available trial information.
