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Recruiting
NCT05918835
Effects of rTMS on Food Choice in Anorexia Nervosa
Conditions: Anorexia Nervosa
Sex: Female
Ages: 18 Years – 35 Years
Healthy volunteers: No
Phase: NA
Enrollment: 72
Sponsor: New York State Psychiatric Institute
Location: New York State Psychiatric Institute New York New York
Summary
This study will examine the impact of high-frequency repetitive transcranial magnetic stimulation on food choice behavior and related neural activity.
Eligibility Criteria
Inclusion Criteria:
* DSM-5 Diagnosis of Anorexia Nervosa
* Age 18-35 years
* Female
* Right-handed
* Body Mass Index (BMI) ≥ 16.0
* Voluntarily admitted to inpatient eating disorders unit at NYSPI
* Competent to provide informed consent
* English-speaking
* Medically stable
Exclusion Criteria:
* High risk of suicide
* Current substance use disorder or other co- morbid psychiatric condition requiring specialized treatment (e.g., psychosis)
* Diagnosis of major medical or neurological problem or taking medication that significantly increases risk for seizure or affects interpretation of findings (e.g., unstable hypertension, seizure disorder)
* Food restrictions (e.g., allergies) which impact greater than 30% of food choice task's choice options
* Indwelling ferromagnetic metallic object (e.g., pacemaker, pump), non- removable metal jewelry, medicinal patch or recent metallic ink tattoo
* History of seizure
* Diagnosis of epilepsy, stroke, multiple sclerosis, traumatic brain injury, Alzheimer's and other neurodegenerative diseases, meningoencephalitis or intracerebral abscess, or parenchymal or leptomeningeal cancers
* Prior exposure to TMS
* Pregnancy
* Currently breast-feeding
* Significant claustrophobia
* Implanted devices or stimulators
* Hearing loss (e.g., currently undergoing treatment with ototoxic medications or those with cochlear implants)
Source: ClinicalTrials.gov (NCT05918835). StuddyBuddy aggregates publicly available trial information.