Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD

Sex: All

Ages: 40 Years – 75 Years

Healthy volunteers: No

Phase: PHASE2

Enrollment: 156

Sponsor: Emory University

Summary

The goals of this project are to investigate the mechanisms and potential therapies related to exercise capacity in persons with chronic kidney disease (CKD).

Eligibility Criteria

Inclusion Criteria: * patients with CKD (Stages III and IV), kidney transplant recipients with varying degrees of kidney function, or persons without kidney disease as matched study controls * sedentary and do not regularly exercise (defined as exercising \< 20 minutes twice per week) * CKD patients must have stable renal function (no greater than a decline of estimated glomerular filtration (eGFR) of 1 cc/min/1.73 m2 per month over the prior 6 months) and baseline serum bicarbonate 22-24 mmol/L * comorbid hypertension Exclusion Criteria: * severe CKD (eGFR\

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05928936). StuddyBuddy aggregates publicly available trial information.