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NCT05938543
Cerebellar TMS and Satiety in Prader-Willi Syndrome
Conditions: Prader-Willi Syndrome
Sex: All
Ages: 18 Years – 64 Years
Healthy volunteers: No
Phase: NA
Enrollment: 20
Sponsor: Brigham and Women's Hospital
Location: McLean Hospital Belmont Massachusetts
Summary
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study hyperphagia and satiety in Prader-Willi syndrome.
TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about how TMS might improve hyperphagia in Prader-Willi syndrome.
Eligibility Criteria
Inclusion Criteria:
* Diagnosis of Prader-Willi syndrome
Exclusion Criteria:
* contraindications for TMS or MRI including :
* history of neurological disorder
* history of head trauma resulting in loss of consciousness
* history of seizures or diagnosis of epilepsy or first degree relative family history of epilepsy
* metal in brain or skull
* implanted devices such as a pacemaker, medication pump, nerve stimulator or ventriculoperitoneal shunt claustrophobic in MRI
Source: ClinicalTrials.gov (NCT05938543). StuddyBuddy aggregates publicly available trial information.