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NCT06077695
Cognitive Remediation of Working Memory Post Head Trauma
Conditions: Head Trauma
Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: No
Phase: NA
Enrollment: 9
Sponsor: University Hospital, Toulouse
Location: UH Toulouse Toulouse
Summary
Patients with working memory deficits due to a moderate to severe head injury will undergo a 5 month protocol including cognitive remediation with numerous exercises, transcranial direct current stimulation (tDCS), and therapeutic education.
Eligibility Criteria
Inclusion Criteria:
* Moderate or severe head trauma, defined by an initial Glasgow score ≤ 12/15, duration of post-traumatic amnesia superior to 24 hours and/or the presence of abnormalities on brain imaging,
* Moderate or severe head trauma occurring within a period greater than or equal to 3 months,
* Working memory complaints assessed by the Working Memory Questionnaire,
* Patients with a working memory disorder in at least one of the following tests: Digit Memory subtest WAIS-IV (standard deviation ≤ -2) , PASAT (percentile ≤ 10), Brown-Peterson (standard deviation ≤ -2).
Exclusion Criteria:
* Presence of aphasia, apraxia or severe neglect demonstrated by standardized neuropsychological tests during the inclusion visit: language - oral naming of BECS-GRECO images, ideational praxis and ideomotor , neglect - bell test,
* Insufficient visual or auditory abilities and oral and written expression to carry out neuropsychological tests,
* Severe depression assessed by the Beck Depression Inventory (BDI)
* Chronic alcoholic poisoning, drug addiction,
* Progressive general illness,
* Progressive psychiatric or neurological condition leading to cognitive impairment,
* Hospitalization for a neurological pathology since the acute phase of the qualifying event,
* Patient requiring surgery during study participation.
* Pregnant or breastfeeding women
Source: ClinicalTrials.gov (NCT06077695). StuddyBuddy aggregates publicly available trial information.