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Recruiting NCT06077695

Cognitive Remediation of Working Memory Post Head Trauma

Conditions: Head Trauma

Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: No
Phase: NA
Enrollment: 9
Sponsor: University Hospital, Toulouse

Location: UH Toulouse Toulouse

Summary

Patients with working memory deficits due to a moderate to severe head injury will undergo a 5 month protocol including cognitive remediation with numerous exercises, transcranial direct current stimulation (tDCS), and therapeutic education.

Eligibility Criteria

Inclusion Criteria: * Moderate or severe head trauma, defined by an initial Glasgow score ≤ 12/15, duration of post-traumatic amnesia superior to 24 hours and/or the presence of abnormalities on brain imaging, * Moderate or severe head trauma occurring within a period greater than or equal to 3 months, * Working memory complaints assessed by the Working Memory Questionnaire, * Patients with a working memory disorder in at least one of the following tests: Digit Memory subtest WAIS-IV (standard deviation ≤ -2) , PASAT (percentile ≤ 10), Brown-Peterson (standard deviation ≤ -2). Exclusion Criteria: * Presence of aphasia, apraxia or severe neglect demonstrated by standardized neuropsychological tests during the inclusion visit: language - oral naming of BECS-GRECO images, ideational praxis and ideomotor , neglect - bell test, * Insufficient visual or auditory abilities and oral and written expression to carry out neuropsychological tests, * Severe depression assessed by the Beck Depression Inventory (BDI) * Chronic alcoholic poisoning, drug addiction, * Progressive general illness, * Progressive psychiatric or neurological condition leading to cognitive impairment, * Hospitalization for a neurological pathology since the acute phase of the qualifying event, * Patient requiring surgery during study participation. * Pregnant or breastfeeding women

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06077695). StuddyBuddy aggregates publicly available trial information.