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Enrolling By Invitation
NCT06089057
Pro-social Power Training Activity for Aging and Well-being With Chronic Kidney Disease
Conditions: Lower Extremity Muscle Strength
Sex: All
Healthy volunteers: No
Phase: NA
Enrollment: 30
Sponsor: VA Office of Research and Development
Location: Tennessee Valley Healthcare System Nashville Campus, Nashville, TN Nashville Tennessee
Summary
This is a pilot trial of a 16-week physical activity and power training program among up to 30 Veterans/arm with advanced chronic kidney disease. The trial aims to test whether the program is tolerable to Veterans.
Eligibility Criteria
Inclusion Criteria:
* Participant's nephrologist and/or primary care physician agree that participant may enroll in trial
* Participants classified as pre-frail per Fried Frailty phenotype due to slowness (time taken to walk 15 feet is greater than 6 seconds) in Aim 1, OR who report 'YES' to any of the following:
* "For health or physical reasons, do you have difficulty in walking a mile (5-6 blocks)?", OR
* "If no, have you changed the way you walk half a mile (5-6 blocks) because of underlying health problems?", OR
* "For health or physical reasons, do you have difficulty in climbing 1 flight of stairs (10 steps)?", OR
* "If no, have you changed the way you climb 1 flight of stairs (10 steps) because of health problems?"
Exclusion Criteria:
* Myocardial infarction or unstable angina within the prior six months based on electronic medical record review or self-report
* Uncontrolled cardiac arrythmia within the prior six months based on electronic medical record review or self-report
* Systolic blood pressure \> 180 mm Hg and/or diastolic blood pressure \> 110 mm Hg on more than one occasion within prior six months based on electronic medical record review or self-report
* Cerebrovascular event and/or transient ischemic attack within prior six months based on electronic medical record review or self-report
* Abnormal cardiac stress test within the past year based on electronic medical record review or self-report
* Hemoglobin of 10 g/dL or less based on electronic medical record review or self-report
* Class IV heart failure based on electronic medical record review or self-report
* Dyspnea and/or chest pain at rest
* Dependence on wheelchair for mobility
* Permanent residence in nursing home or other long-term care facility
* Terminal illness or other hospice-qualifying medical condition
* Planned move away from middle Tennessee within the next year
* Planned major surgery in the next six months
* Blindness
* Concurrent enrollment in physical therapy or structured exercise program
* Anticipated dialysis or kidney transplant in upcoming three months
* Non-English speaking
* Severe cognitive impairment based on electronic medical record review or self-report
Source: ClinicalTrials.gov (NCT06089057). StuddyBuddy aggregates publicly available trial information.