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Active Not Recruiting
NCT06193499
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
Conditions: Osteoarthritis Thumb
Sex: All
Healthy volunteers: No
Phase: NA
Enrollment: 90
Sponsor: Karolinska Institutet
Location: Department of Hand Surgery Södersjukhuset Stockholm
Summary
This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.
Eligibility Criteria
Inclusion Criteria:
* Osteoarthritis in the thumb base
* Radiological Eaton Littler class 1-3.
* Clinical signs of thumb base osteoarthritis )pain at palpation of the CMC-1 joint and pain during provocation/grinding test).
Exclusion Criteria:
* Rheumatoid arthritis
* Ongoing infection in the hand or wrist
* History of gout or pseudogout in the hand
* Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction).
* Chronic pain syndrome / centralized pain.
* Intra-articular injection in the affected joint within 6 months.
* Eaton Littler class 4 (symptomatic STT joint osteoarthritis).
Source: ClinicalTrials.gov (NCT06193499). StuddyBuddy aggregates publicly available trial information.
