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Active Not Recruiting
NCT06214936
Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield
Conditions: Infertility
Sex: Female
Ages: 18 Years – 41 Years
Healthy volunteers: No
Phase: NA
Enrollment: 252
Sponsor: Reproductive Medicine Associates of New Jersey
Location: Reproductive Medicine Associates of New Jersey Basking Ridge New Jersey
Summary
The goal of this study is to determine if benchtop incubators improve the number of embryos making it to the blastocyst stage of development (about 4-6 days after fertilization) in people undergoing in vitro fertilization (IVF) treatment for their infertility.
* Test the effectiveness of the benchtop incubator.
* Determine if the number of embryos reaching the blastocyst stage of embryo development (the stage that the embryos are biopsied for PGT-A and frozen) is improved in the benchtop incubator compared to the box incubator.
* Compare embryology outcomes between the two incubator types.
* Investigate transfer and pregnancy outcomes.
* Expand the knowledge surrounding the impact of the incubator on IVF outcomes. Patients will have their mature oocytes collected at the egg retrieval procedure split into two groups and randomized to be cultured in both incubator types.
Eligibility Criteria
Inclusion Criteria for participants:
1. Patients undergoing an IVF cycle with plan for subsequent frozen embryo transfer (FET) of a single euploid embryo
2. 4 mature oocytes prior to randomization
3. Female partners age \
Source: ClinicalTrials.gov (NCT06214936). StuddyBuddy aggregates publicly available trial information.