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Active Not Recruiting NCT06272123

Endotypic Stability in CRS

Conditions: Chronic Sinusitis

Sex: All

Ages: 18 Years – 100 Years

Healthy volunteers: No

Enrollment: 200

Sponsor: Thomas Jefferson University

Location: Thomas Jefferson University Department of Otolaryngology Philadelphia Pennsylvania

Summary

A Case control study with 150 cases and 50 controls will be conducted. Immunologic (cytokines measurements in nasal secretions and sinonasal tissues), histopathologic (tissue eosinophilia) and clinical parameters (Lund-Mackay and Lund-Kennedy score, lung function tests), surveys (SNOT- 22, SF-36 quality of life survey) will be compared between different groups of patients

Eligibility Criteria

Inclusion Criteria: * Patients with Chronic sinusitis (with or without polyps) * Undergoing endoscopic sinus surgery during the study period * More than 18 years * No chronic illness/ malignancy

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06272123). StuddyBuddy aggregates publicly available trial information.