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Recruiting
NCT06273072
Metformin IN Asthma for Overweight and Obese Individuals (MINA)
Conditions: Asthma, Asthma Chronic, Overweight and Obesity
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE2
Enrollment: 100
Sponsor: Johns Hopkins University
Location: Johns Hopkins University Baltimore Maryland
Summary
This is a randomized clinical trial of metformin among overweight or obese adults with not well-controlled asthma despite maintenance inhaler therapy.
Eligibility Criteria
Inclusion Criteria:
* Physician-diagnosed asthma on maintenance therapy
* Not well-controlled asthma (ACT score \ 2x the upper limit of normal or prior diagnosis of liver disease
* Anemia: hemoglobin \< 13 g/dl in males and hemoglobin \< 11 g/dl in females
* Taking Glucagon Like Peptide 1(GLP-1) medications for weight loss
* Diabetes (Hemoglobin A1C ≥ 6.5% or taking metformin or other medications used to treat diabetes)
* Participation in any other clinical trial (observational studies are permitted)
Source: ClinicalTrials.gov (NCT06273072). StuddyBuddy aggregates publicly available trial information.