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NCT06280677
Aurora Test for ART Donor Patients (AURORA-Donor)
Conditions: Infertility
Sex: Female
Ages: 18 Years – 35 Years
Healthy volunteers: Yes
Enrollment: 160
Sponsor: Fertiga, Belgium
Location: Fertilab Barcelona
Summary
This is a randomized observational study. The main aim is to determine potential oocyte competence predictive mRNA expression profiles in the cumulus cells isolated form individual oocytes. In 2 patient cohorts: 1)GnRH Antagonist \& hr-FSH with GnRH Agonist trigger, 2) Progesterone \& hr-FSH with GnRH Agonist trigger.
Eligibility Criteria
Inclusion Criteria Donor:
* Patients are 18 to 35 years old
* BMI between 17-30
* Regular menstrual cycles
* AFC \> 8
* Patient profile in compliance with SEF (Sociedad Española de Fertilidad) directives for egg donation (medical, psychological and genetic screening, informed consent)
* Patients' stimulation: GnRH Antagonist \& hr-FSH with GnRH Agonist trigger or Progesterone \& hr-FSH with GnRH Agonist trigger
* Patients agree that the oocytes will be denuded for cumulus testing and provide written informed consent for participation to the study
Exclusion Criteria Donor:
* BMI \< 17 or \> 30
* Extreme irregular menstrual cycles (\40 days)
* AFC \< 8
* \
Source: ClinicalTrials.gov (NCT06280677). StuddyBuddy aggregates publicly available trial information.