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Completed
NCT06283472
Enhancing Prospective Thinking in Early Recovery (BEAM)
Conditions: Alcohol Use Disorder
Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: No
Phase: NA
Enrollment: 22
Sponsor: Indiana University
Location: Indiana University School of Medicine - Goodman Hall Indianapolis Indiana
Summary
The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question\[s\] this trial aims to answer are:
* Will high-intensity EFT cues will produce greater delayed reward preference than low-intensity cues?
* Will high-intensity EFT cues effect greater treatment-seeking interest?
* Will high-intensity EFT cues elicit greater response in regions for prospective thinking during delay discounting (vs. low-intensity)
* Will nucleus accumbens-precuneus resting connectivity correlate with behavioral SS?
* Will the novel behavioral SS decision-making task activate the nucleus accumbens?
Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.
Eligibility Criteria
Inclusion Criteria:
* Individuals who meet current heavy drinking (≥2 heavy drinking days/month OR ≥7 drinks/week for biological females, and ≥14 drinks/week if biological male \[NIAAA definition\] and/or AUDIT scores ≥8)
* English comprehension
Exclusion Criteria:
* Unstable medical disorders
* Outside the age range of 18-60
* Smell/taste disorders
* Unstable psychiatric conditions
Source: ClinicalTrials.gov (NCT06283472). StuddyBuddy aggregates publicly available trial information.