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NCT06289478
Efficacy and Safety of Topical Tranexamic Acid (TXA) Administration Cementless Bipolar Hemiarthroplasty for Femoral Neck Fracture - a Randomized Controlled Trial
Conditions: Femoral Neck Fracture
Sex: All
Ages: 60 Years – N/A
Healthy volunteers: Yes
Phase: NA
Enrollment: 75
Sponsor: King Chulalongkorn Memorial Hospital
Location: Faculty of Medicine, King Chulalongkorn Memorial Hospital Bangkok Bangkok
Summary
The goal of this Randomized controlled trial is to evaluate in household ambulatory, elderly patients sustaining femoral neck fracture who are subjected to be treat with cementless bipolar hemiarthroplasty. The main questions it aims to answer are:
* The efficacy in reducing blood transfusion for topical tranexamic acid administration
* The safety of tranexemic acid, topically used
As having undergone bipolar hemiarthroplasty surgery, participants will either receive retrograde intraarticular tranexamic acid injection via drain tube, or topical soaking administration.
Researchers will compare, with standard procedure (procedure), whether topically administered tranexamic acid would reduce rate of blood transfusion.
Eligibility Criteria
Inclusion Criteria:
* Elderly patients (age \> 60 years)
* Femoral neck fractures from low energy mechanism
* Household ambulator
* Undergoing cementless bipolar hemiarthroplasty at KCMH
* Informed consent
Exclusion Criteria:
* Allergy to TXA
* History of VTE
* History of hip surgery, pathological fracture, hip infection
* Congenital or acquired coagulopathy
* Hb \< 10 g/dL or Platelet \< 140,000
Source: ClinicalTrials.gov (NCT06289478). StuddyBuddy aggregates publicly available trial information.