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Recruiting NCT06289478

Efficacy and Safety of Topical Tranexamic Acid (TXA) Administration Cementless Bipolar Hemiarthroplasty for Femoral Neck Fracture - a Randomized Controlled Trial

Conditions: Femoral Neck Fracture

Sex: All
Ages: 60 Years – N/A
Healthy volunteers: Yes
Phase: NA
Enrollment: 75
Sponsor: King Chulalongkorn Memorial Hospital

Location: Faculty of Medicine, King Chulalongkorn Memorial Hospital Bangkok Bangkok

Summary

The goal of this Randomized controlled trial is to evaluate in household ambulatory, elderly patients sustaining femoral neck fracture who are subjected to be treat with cementless bipolar hemiarthroplasty. The main questions it aims to answer are: * The efficacy in reducing blood transfusion for topical tranexamic acid administration * The safety of tranexemic acid, topically used As having undergone bipolar hemiarthroplasty surgery, participants will either receive retrograde intraarticular tranexamic acid injection via drain tube, or topical soaking administration. Researchers will compare, with standard procedure (procedure), whether topically administered tranexamic acid would reduce rate of blood transfusion.

Eligibility Criteria

Inclusion Criteria: * Elderly patients (age \> 60 years) * Femoral neck fractures from low energy mechanism * Household ambulator * Undergoing cementless bipolar hemiarthroplasty at KCMH * Informed consent Exclusion Criteria: * Allergy to TXA * History of VTE * History of hip surgery, pathological fracture, hip infection * Congenital or acquired coagulopathy * Hb \< 10 g/dL or Platelet \< 140,000

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06289478). StuddyBuddy aggregates publicly available trial information.