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Completed
NCT06323057
Modulating Reward Learning Using Transcranial Magnetic Stimulation
Conditions: Behavior
Sex: All
Ages: 18 Years – 55 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 36
Sponsor: Rutgers, The State University of New Jersey
Location: Rutgers University - Newark Newark New Jersey
Summary
Our specific aim is to examine the effects of single TMS pulse on reward processing during goal-directed behavior. In these experiments the investigators will utilize a scalp-recorded brain oscillation called frontal midline theta that is believed to index the sensitivity of the cingulate cortex to reward feedback. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in decision making tasks, and if so, whether it would affect the encoding of rewards and subsequent choices during task performance.
Eligibility Criteria
Inclusion Criteria:
* Be between the ages of 18 and 55 years old.
* Be in stable mental and physical health.
* If female, test non-pregnant.
* Be willing to provide informed consent.
* Be able to comply with protocol requirements and likely to complete all study procedures.
Exclusion Criteria:
* Contraindication to rTMS (history of neurological disorder or seizure, increased intracranial pressure, brain surgery, or head trauma with loss of consciousness for \> 15 minutes, implanted electronic device, metal in the head, or pregnancy).
* History of autoimmune, endocrine, viral, or vascular disorder affecting the brain.
* Life time history of mental disorders such as: Bipolar Affective disorder (BPAD), Schizophrenia, Post-traumatic Stress disorder (PTSD) or Dementia or Major Depression.
* uninterruptable central nervous system medication
Source: ClinicalTrials.gov (NCT06323057). StuddyBuddy aggregates publicly available trial information.