A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

The purpose of this study is to compare the plasma pharmacokinetics (PK) of nemtabrutinib (MK-1026) following a single oral dose of nemtabrutinib in participants with moderate hepatic impairment to that of healthy matched control participants and to evaluate the safety and tolerability of nemtabrutinib.

Inclusion Criteria: * Has a body mass index (BMI) between 18.0 and 40.0 kg/m2, inclusive. * Is assigned male or female sex at birth. Participants assigned female sex at birth must not be pregnant or breast feeding and must be of nonchild bearing potential. * Who agrees to use contraception. * Has provided documented informed consent for the study. * Has a diagnosis of chronic (\>6 months), stable (no acute episodes of illness within the previous 2 months due to deterioration in hepatic function) hepatic impairment with features of cirrhosis due to any etiology (moderate HI only). * Has moderate hepatic impairment (class B) by the Child-Pugh classification system AND/OR the participant has moderate impairment by the National Cancer Institution Organ Dysfunction Working Group (NCI-ODWG) classification system (moderate HI only). * Is in general good health (except for Moderate HI). Exclusion Criteria: * Has a clinically significant condition that may affect absorption of the study drug in the opinion of the investigator, including gastric restrictions and bariatric surgery (eg, gastric bypass). * Is mentally or legally incapacitated, has significant emotional problems at the time of prestudy (screening) visit or expected during the conduct of the study or has a history of clinically significant psychiatric disorder of the last 5 years. * Has a history of cancer (malignancy). * Has a history of significant multiple and/or severe allergies (eg, food, drug, latex allergy), or has had an anaphylactic reaction or significant intolerability (systemic allergic reaction) to prescription or nonprescription drugs or food. * Had a major surgery and/or donated or lost 1 unit of blood (approximately 500 mL) within 4 weeks prior to the prestudy. * Has received any vaccine starting from 14 days prior to study or is scheduled to receive any vaccine through 30 days following study intervention. * Was dosed in another investigational study within 4 weeks (or 5 half-lives, whichever is greater) prior to check-in (Day -1). * Is under the age of consent. * Is heavy smoker or heavy user of nicotine-containing products (\>20 cigarettes or equivalent/day). * Is regular user of cannabis or any illicit drugs or has a history of drug (including alcohol) abuse within approximately 3 months. * Consumes greater than 3 servings of alcoholic beverages per day. * Consumes excessive amounts, defined as greater than 6 servings of coffee, tea, cola, (1 serving is approximately equivalent to 120 mg of caffeine) energy drinks, or other caffeinated beverages per day. * Is unwilling to comply with the study restrictions. * Has a history or illness that in the opinion of the investigator, might confound the results of the study or poses an additional risk to the participant by their participation in the study (moderate HI only). * Has a history of recent variceal bleeds (for moderate HI only). * Has evidence of hepatorenal syndrome (for moderate HI only). * Has fluctuating or rapidly deteriorating hepatic function within the prestudy period, in the opinion of the investigator (for moderate HI only). * Is not in sufficient health, with regard to stability of HI, to undergo participation in the study with anticipated survival of \