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Recruiting
NCT06502158
Mifepristone vs Misoprostol
Conditions: Cervical Preparation
Sex: Female
Ages: 18 Years – 45 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 94
Sponsor: Montefiore Medical Center
Location: Montefiore Medical Center The Bronx New York
Summary
The Investigator team hypothesizes that in a randomized trial comparing mifepristone-alone or misoprostol-alone for cervical preparation for procedural abortions at 12 to 16 weeks in hospital-based care, the proportion of patients who achieve successful cervical dilation will be different between the study groups.
Eligibility Criteria
Inclusion Criteria:
* English or Spanish-speaking
* Capacity to consent
* Seeking induced abortion of a singleton pregnancy between 12 weeks, 0 days and 16 weeks, 6 days (based on age at day of surgery)
Exclusion Criteria:
* History of more than two prior Cesarean deliveries
* Sonographic evidence of placenta previa
* Sonographic concern for morbidly adherent placenta
* Prior obstetric hemorrhage requiring transfusion
* Obstructive cervical or lower uterine segment fibroid
* Current therapeutic anticoagulation use
* Cerclage in situ
* History of more than one prior cervical excisional procedure
* BMI greater than 50 kg/m\^2
Source: ClinicalTrials.gov (NCT06502158). StuddyBuddy aggregates publicly available trial information.