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Completed NCT06514703

Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis

Conditions: Osteoarthritis, Knee

Sex: All
Ages: 45 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 80
Sponsor: Zagazig University

Location: Zagazig University, Faculty of Medicine Zagazig Sharqia Province

Summary

The goal of this study is to evaluate the comparative effectiveness of CT-guided and fluoroscopic-guided genicular nerve ablation in reducing knee pain and improving function in adults diagnosed with knee osteoarthritis refractory to conservative treatment. The main questions it aims to answer are: * Does CT-guided genicular nerve ablation provide superior pain relief compared to fluoroscopic-guided genicular nerve ablation? * Is there a significant difference in functional improvement between the two techniques? Researchers will compare the outcomes between the CT-guided and fluoroscopic-guided groups to determine which method achieves better pain relief, functional enhancement, safety profile, and patient satisfaction. Participants will: * Undergo either CT-guided or fluoroscopic-guided genicular nerve ablation. * Attend scheduled follow-up visits to assess pain levels, knee function, and any adverse events. * Complete standardized questionnaires to provide feedback on pain relief, functional improvement, and overall satisfaction with the procedure.

Eligibility Criteria

Inclusion Criteria: * Adults aged 45 to 80 years. * Diagnosed with knee osteoarthritis. * Knee osteoarthritis refractory to conservative treatment. * Able to provide informed consent. * Agree to follow the study procedures and attend follow-up visits. Exclusion Criteria: * Prior knee surgery within the last six months. * Contraindications to genicular nerve ablation (e.g., certain types of infections, bleeding disorders). * Severe comorbid conditions that may interfere with the study outcomes (e.g., rheumatoid arthritis, other severe autoimmune diseases). * Current participation in another clinical trial that could interfere with the outcomes of this study. * Allergy or sensitivity to the materials used in the ablation procedures.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06514703). StuddyBuddy aggregates publicly available trial information.