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Completed
NCT06514703
Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis
Conditions: Osteoarthritis, Knee
Sex: All
Ages: 45 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 80
Sponsor: Zagazig University
Location: Zagazig University, Faculty of Medicine Zagazig Sharqia Province
Summary
The goal of this study is to evaluate the comparative effectiveness of CT-guided and fluoroscopic-guided genicular nerve ablation in reducing knee pain and improving function in adults diagnosed with knee osteoarthritis refractory to conservative treatment.
The main questions it aims to answer are:
* Does CT-guided genicular nerve ablation provide superior pain relief compared to fluoroscopic-guided genicular nerve ablation?
* Is there a significant difference in functional improvement between the two techniques?
Researchers will compare the outcomes between the CT-guided and fluoroscopic-guided groups to determine which method achieves better pain relief, functional enhancement, safety profile, and patient satisfaction.
Participants will:
* Undergo either CT-guided or fluoroscopic-guided genicular nerve ablation.
* Attend scheduled follow-up visits to assess pain levels, knee function, and any adverse events.
* Complete standardized questionnaires to provide feedback on pain relief, functional improvement, and overall satisfaction with the procedure.
Eligibility Criteria
Inclusion Criteria:
* Adults aged 45 to 80 years.
* Diagnosed with knee osteoarthritis.
* Knee osteoarthritis refractory to conservative treatment.
* Able to provide informed consent.
* Agree to follow the study procedures and attend follow-up visits.
Exclusion Criteria:
* Prior knee surgery within the last six months.
* Contraindications to genicular nerve ablation (e.g., certain types of infections, bleeding disorders).
* Severe comorbid conditions that may interfere with the study outcomes (e.g., rheumatoid arthritis, other severe autoimmune diseases).
* Current participation in another clinical trial that could interfere with the outcomes of this study.
* Allergy or sensitivity to the materials used in the ablation procedures.
Source: ClinicalTrials.gov (NCT06514703). StuddyBuddy aggregates publicly available trial information.