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Recruiting
NCT06538636
Prediction Augmented Screening Initiative
Conditions: Lung Cancer, Lung Cancer Screening
Sex: All
Ages: 50 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 23520
Sponsor: VA Office of Research and Development
Location: VA Bedford HealthCare System, Bedford, MA Bedford Massachusetts
Summary
Lung cancer is responsible for more deaths in the United States than breast, prostate and colon cancer combined and is the number one cancer killer of Veterans. This is because lung cancer is usually diagnosed when the disease has spread, and cure is less likely. Lung cancer screening (LCS) finds cancer at an earlier stage when it is curable, yet only 20% of eligible Veterans have been screened. Uptake is even lower among Black Veterans despite higher lung cancer risk. Using prediction models to identify high-benefit people for whom LCS should be encouraged improves efficiency and reduces disparities. Moreover, it is more patient-centered as shared decision-making conversations can be tailored with personalized information. The US Preventive Services Task Force has called for research to demonstrate that prediction-augmented LCS can be feasibly implemented at the point-of-care. The investigators propose for VA to lead this effort with a large-scale pragmatic clinical trial to show that prediction-augmented LCS is both feasible and improves LCS uptake.
Eligibility Criteria
Inclusion Criteria:
Veterans assigned a PCP at a participating site and who meet inclusion criteria at any point during the study timeframe will be enrolled into the trial. There will be two paths to patient inclusion:
* meeting USPSTF eligibility criteria for LCS, as currently encoded in the background logic of LCS clinical reminders maintained by the VA National Center for Lung Cancer Screening (i.e., age 50-80 years; smoked 20 pack-years; current smoking or quit \
Source: ClinicalTrials.gov (NCT06538636). StuddyBuddy aggregates publicly available trial information.