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Completed
NCT06576297
Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart Failure
Conditions: Aging, Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection Fraction, Frailty, Physical Function, Quality of Life
Sex: All
Ages: 70 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 20
Sponsor: University of Pittsburgh
Location: University of Pittsburgh Pittsburgh Pennsylvania
Summary
In a randomized controlled trial, to study the utility of inspiratory muscle training (IMT) to improve functional outcomes in adults aged ≥70 years with heart failure (HF) who have been referred to palliative care for end-stage HF management.
* The study team hypothesize that older HF patients will be able to use IMT safely, reliably, and effectively in a 12-week home-based training regimen.
* The study team hypothesize that physical function (sit to stand, gait speed, grip strength), respiratory/pulmonary function, self-efficacy, fatigue and quality of life will increase among older HF patients randomized IMT versus those randomized to usual care.
Eligibility Criteria
Inclusion Criteria:
* Patients with Advanced Heart Failure (HFrEF or HFpEF), with NYHA class II, III, or IV despite a minimum of
* 6 weeks of treatment
* Age \>70 years
* Male and Female
* Optimal therapy according to AHA/ACC and HFSA HF guidelines
Exclusion Criteria:
* Patients living in an institutional setting (e.g., skilled nursing home) during the intended period of this study.
* Major cardiovascular event or procedure within the prior 6 weeks.
* HF secondary to significant uncorrected primary valvular disease (except mitral regurgitation secondary to left ventricular dysfunction). If valve replacement has been performed, the participant may not be enrolled for 12 months after this procedure.
* Dementia
* Severe COPD (FEV1\
Source: ClinicalTrials.gov (NCT06576297). StuddyBuddy aggregates publicly available trial information.