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NCT06576310
Predictive Factors for Occlusal Changes in Obstructive Sleep Apnea Treatment With Mandibular Advancement Appliance
Conditions: Obstructive Sleep Apnea Syndrome
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 118
Sponsor: University Hospital, Toulouse
Location: University Hospital of Toulouse Toulouse
Summary
This research addresses obstructive sleep apnea syndrome (OSAS), affecting 6-12% of French adults, often treated with mandibular advancement devices (MADs). MADs may lead to occlusal modifications, causing a 50% treatment abandonment rate. The study employs surface electromyography to assess masticatory muscle activity before and during MAD use, correlating it with occlusal changes after 6 months. The primary goal is to determine dental displacement profiles post-6-month MAD treatment, providing insights for personalized care and minimizing treatment failures.
Eligibility Criteria
Inclusion Criteria:
* Patient with complete dentition (up to second molars)
* Polysomnography or polygraphy
* Diagnosis of OSA
* Patient receiving OAM treatment at the Odontology Department of Toulouse University Hospital
* Patient with contemporary panoramic and lateral cephalometric X-rays (common practice) taken at the time of orthotic treatment
* Individual affiliated with or covered by a social security scheme
* Voluntary, informed, written consent, signed by both participant and investigator (prior to inclusion and any necessary research-related examinations).
Exclusion Criteria:
* Inability to provide informed consent
* Pregnant or breastfeeding patient
* Patient with curators, guardians, or legal protection
Source: ClinicalTrials.gov (NCT06576310). StuddyBuddy aggregates publicly available trial information.