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Recruiting
NCT06582810
Lidocaine Infusion Treatment for Subarachnoid Hemorrhage Headaches
Conditions: Subarachnoid; Hemorrhage, Nontraumatic, Headache
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 20
Sponsor: University of Kansas Medical Center
Location: Ascension Via Christi St. Francis Wichita Kansas
Summary
The goal of this observational study is to evaluate intravenous lidocaine efficacy and safety in treating headache following non-traumatic subarachnoid hemorrhage. Through this prospective analysis, the investigators hope to:
1. show that intravenous lidocaine infusion causes a clinically significant reduction in pain scores in patients with moderate/severe headache pain following non-traumatic subarachnoid hemorrhage;
2. show that intravenous lidocaine infusion is safe in treating headache following non-traumatic subarachnoid hemorrhage;
3. and report vasospasm prevalence in the cohort.
Participants will receive lidocaine infusion as treatment for non-traumatic subarachnoid hemorrhage headache and provide pain scores (on a numeric pain scale) every two hours the patients are awake for a maximum of seven days. Monitoring for vasospasm will occur as part of the patients regular medical care.
Eligibility Criteria
Inclusion Criteria:
* Patients \> 18 years;
* Have a favorable neurological status defined as Hunt and Hess score ≤ 3 (as it accounts for patient awareness);
* Can communicate numeric pain scores;
* Are diagnosed with non-traumatic subarachnoid hemorrhage
Exclusion Criteria:
* The patient is diagnosed with traumatic subarachnoid hemorrhage;
* If the patient is \< 18 years of age;
* If numeric pain scores could not be captured for \> 3 days of hospitalization;
* If the patient had a prior aneurysm;
* Chronic pain not associated with non-traumatic subarachnoid hemorrhage diagnosis;
* A disability before the stroke (\> 2 on modified Rankin Scale score);
* A Hunt and Hess score \> 3;
* Contraindications to lidocaine (significant cardiac disease, arrhythmia, seizures, previous allergic reaction to lidocaine
Source: ClinicalTrials.gov (NCT06582810). StuddyBuddy aggregates publicly available trial information.