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Recruiting
NCT06619912
Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery Patients
Conditions: Postoperative Delirium, Preoperative Sleep Disorder
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE3
Enrollment: 686
Sponsor: Xijing Hospital
Location: Xijing Hospital Xi'an Shaanxi
Summary
Delirium is a common consequence of cardiac surgery and associates with poor outcomes. Multiple causes can trigger delirium occurence, and it has been hypothesised that sleep disturbances can be one of them. Dexmedetomidine may be effective in reducing delirium. The aim of this study was to demonstrate preoperative dexmedetomidine nasal spray in cardiac surgery patients can reduce postoperative delirium by improving preoperative sleep.
Eligibility Criteria
Inclusion Criteria:
1. Aged 18 years or older.
2. Cardiac surgery with cardiopulmonary bypass.
3. Ability to provide consent.
Exclusion Criteria:
1. Preoperative schizophrenia, epilepsy, Parkinson's disease, myasthenia gravis, history of neurosurgery, or Mini-mental State Examination(MMSE) score: illiteracy\
Source: ClinicalTrials.gov (NCT06619912). StuddyBuddy aggregates publicly available trial information.
