Proteomic Analysis on Myopic Children Using Orthokeratology Lenses With Good or Poor Myopic Control

The key objective of the study is to gain an understanding of the biochemical processes that contribute to orthokeratology lenses being more effective in specific individuals compared to others. With this knowledge, we hope to optimize treatment effectiveness in those currently experiencing less favorable outcomes from treatment in the future. The primary aim is to investigate differences in protein levels in children using orthokeratology lenses with various effects of myopia control. Hypothesis: There is a significant difference in the expression of molecules in children with various effects of myopia control.

Inclusion Criteria: * Children treated with orthokeratology lenses. * Children on or above the 95th percentile of myopia growth curves for European children at the time of treatment initiation. * Treatment and follow-up duration ≥ 6 months. Exclusion Criteria: * Current use of eye drops. * Objective signs of dry eyes on slit-lamp examination. * Active eye infection.