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Completed NCT06679959

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ASC30 Injection in Participants With Obesity

Conditions: Chronic Weight Management

Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Phase: PHASE1, PHASE2
Enrollment: 115
Sponsor: Ascletis Pharma (China) Co., Limited

Location: Ascletis clinical site San Antonio Texas

Summary

This randomized, double-blind, placebo-controlled single ascending dose (SAD)/ multiple ascending dose (MAD) study is designed to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ASC30 injection

Eligibility Criteria

Inclusion Criteria: 1. Have provided informed consent before initiation of any study-specific procedures. 2. Male or female participants, non-smokers, between 18 and 65 years of age (both inclusive). 3. No clinically significant findings from medical history, physical examination, 12-lead ECG, vital signs measurements, and other screening procedures. Exclusion Criteria: 1. Have evidence of any clinically significant active or chronic disease. 2. Have any prior diagnosis of diabetes mellitus (T1DM or T2DM), or rare forms of diabetes mellitus. 3. Have an autoimmune disease, is immunosuppressed or is in any way immunocompromised. 4. Have a history of acute or chronic pancreatitis. 5. Participants with a known clinically significant gastric emptying abnormality. 6. Have a history of an active or untreated malignancy or are in remission from a clinically significant malignancy. 7. Have a history of any other condition (such as known drug or alcohol abuse, diagnosed eating disorder, or other psychiatric disorder) that, in the opinion of the Investigator, may preclude the participant from following and completing the protocol.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06679959). StuddyBuddy aggregates publicly available trial information.