← Back to all trials
Completed
NCT06697847
Sweet Thresholds in Healthy Volunteers Study
Conditions: Taste Thresholds in Healthy Volunteers
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: Yes
Enrollment: 30
Sponsor: Ranvier Health Ltd
Location: Westbury Lodge, Westbury Park Bristol City Of Bristol
Summary
The sweet threshold (concentration of sucrose in water) at which healthy participants can detect a sweet flavour will be recorded.
Eligibility Criteria
Inclusion Criteria:
. Male and female adults of 18 years old and over;
* Participants without a diagnosis of major depressive disorder (MDD) / anxiety disorder;
* Participants not taking an antidepressant during the preceding 6 months
* Not suffering from significant other mental or physical illness, such as confirmed psychosis, end of life care, or any other condition assessed as significant by the Site Investigator;
* Willing and able to comply with all study-related procedures;
* Not having COVID 19 or continuing effects of COVID 19 including altered sense of taste;
* Understands the study requirements and the treatment procedures and is able to provide written informed consent.
Exclusion Criteria:
* Taking antidepressant medication currently or during the previous 6 months;
* Known or suspected hypersensitivity or intolerance to any taste testing solutions, or any of their excipients;
* A history or presence of neurological or confounding psychiatric conditions (such as stroke, traumatic brain injury, epilepsy, space occupying lesions, multiple sclerosis, Parkinson's disease, vascular dementia, transient ischemic attack, or schizophrenia);
* Patients with a diagnosis of chronic pain;
* Pregnancy or possibility pregnancy, or breastfeeding;
* Participants using supplements containing psychoactive herbs (for example St Johns Wort or 5-HTP (5-Hydroxytryptophan, also known as oxitriptan);
* Participants regularly using psychoactive stimulants (for example MDMA);
* Participants unable or unwilling to comply with study procedures.
Source: ClinicalTrials.gov (NCT06697847). StuddyBuddy aggregates publicly available trial information.