Evaluation of a Long Versus Short Clomid Protocol for Controlled Ovarian Stimulation

Sex: Female

Ages: 18 Years – 44 Years

Healthy volunteers: No

Phase: PHASE4

Enrollment: 120

Sponsor: University of Southern California

Summary

The goal of this clinical trial is to evaluate a long Clomid protocol as compared to a 5-day Clomid protocol for ovarian stimulation in patients with diminished ovarian reserve undergoing ovarian stimulation for in-vitro fertilization. The aim of the long Clomid protocol is to intensify stimulation of the ovaries and reduce both cost and injection burden for patients. Participants will be randomized to receive the long Clomid protocol vs. the typical protocol involving Clomid only for 5 days followed by growth hormone-releasing hormone (GnRH) antagonist. The primary outcome the investigators will evaluate will be the number of mature eggs retrieved.

Eligibility Criteria

Inclusion Criteria: * Undergoing IVF * Must meet POSEIDON criteria based on clinic evaluation * Female partner: Antral follicle count of 2 or more and age \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06701071). StuddyBuddy aggregates publicly available trial information.