← Back to all trials
Completed
NCT06802354
Efficacy of Ozone Therapy in Reducing Complications Following Impacted Mandibular Third-molar Surgery
Conditions: Impacted Mandibular Third Molar Extraction
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE3
Enrollment: 20
Sponsor: Jelena Krunic
Location: University of East Sarajevo, Faculty of Medicine Foca Republika Srpska
Summary
The goal of this clinical trial is to learn if use of ozone works to treat complications after impacted mandibular third molar surgery. It will also learn does ozone has positive effect on wound healing and quality of life.
The main questions it aims to answer are:
* Does ozone reduce incidence of postoperative compliactions such as pain, swelling or reduced mouth opening after impacted mandibular third molar surgery?
* Does ozone improve wound healing after impacted mandibular third molar surgery?
* Does ozone have positive effect on quality of life after impacted mandibular third molar surgery?
Participants will:
* Receive ozone after impacted mandibular third molar surgery.
* Visit the clinic 1st, 3rd, and 7th days after the intervention for checkups and tests.
* Keep a diary of their symptoms.
Eligibility Criteria
Inclusion Criteria:
* Patients over 18 years
* Patients with bilaterally impacted mandibular third molars classified as impaction index II B
* Patients in good general health (based on the ASA classification as ASA I and ASA II).
Exclusion Criteria:
* Contraindications for ozone application (pregnancy, hyperthyroidism, favism, anemia, myasthenia, bleeding disorders, alcohol intoxication, myocardial infarction, pacemaker, allergy to ozone)
* Patients who have used corticosteroid and antibiotic therapy in the last three months prior to inclusion in the study
* Patients with signs of local inflammation in the oral cavity
* Female patients during pregnancy and breastfeeding.
Source: ClinicalTrials.gov (NCT06802354). StuddyBuddy aggregates publicly available trial information.