Correlation Between Clinical Neurological Biomarkers and Rehabilitation Outcome

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 300

Sponsor: IRCCS San Raffaele Roma

Summary

Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor functional recovery and disability post-stroke. The goal is to construct an integrated individual biomarker algorithm with a high predictive value for outcomes.

Eligibility Criteria

Inclusion Criteria: * First stroke in the middle cerebral artery territory. * Ischemic or hemorrhagic stroke (7-30 days post-acute event). * Upper limb plegia or paresis. * Both genders, aged \>18 years. * Ability to provide informed consent by the patient or caregiver/responsible relative. Exclusion Criteria: * Previous stroke. * Stroke in territories other than the middle cerebral artery. * Inability to provide informed consent. * Contraindications to TMS or MRI. * History of cancer in the past two years. * Presence of other neurological conditions interfering with biomarkers

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06805929). StuddyBuddy aggregates publicly available trial information.