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NCT06836141
Biomarkers for Cognitive Decline in Intracerebral Hemorrhage
Conditions: Primary Intracerebral Hemorrhage
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Enrollment: 118
Sponsor: Rush University Medical Center
Location: Rush University Medical Center Chicago Illinois
Summary
The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are
* if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline
* if SBIs in sICH are associated with certain findings on brain imaging
* if SBIs in sICH are associated with higher inflammation measured by certain blood tests
Participants will undergo
* cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH
* Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH
* blood draws during hospitalization and at 3, 6 and 12 months after the sICH
Eligibility Criteria
Inclusion Criteria:
* Primary Intracerebral Hemorrhage
* Age ≥ 18 and \< 80 years
Exclusion Criteria:
* Pre-existing dementia
Source: ClinicalTrials.gov (NCT06836141). StuddyBuddy aggregates publicly available trial information.