Pre-malignant States to Hematologic Malignancies in Firefighters

Conditions: Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy, Non Hodgkin Lymphoma, Leukemia, Multiple Myeloma, Plasma Cell Disorder

Sex: All

Ages: 40 Years – 49 Years

Healthy volunteers: Yes

Enrollment: 300

Sponsor: Wake Forest University Health Sciences

Summary

The purpose of the study is to evaluate if firefighter exposure to hazardous compounds will increase the incidence of premalignant hematological states which subsequently increases the risk of the development of hematologic malignancies, and potentially other pathophysiological consequences.

Eligibility Criteria

Inclusion Criteria: 1. Written informed consent and HIPAA authorization for release of personal health information. 2. Age ≥ 40-49 years at the time of consent (self-reported) 3. Ability of the participant to understand and comply with study procedures for the entire length of the study 4. Currently employed by Charlotte Fire Department (CFD) with at least 5 years on-the -job experience (self-reported) Exclusion Criteria: Anyone with a current diagnosis of a hematologic malignancy will be excluded.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06870760). StuddyBuddy aggregates publicly available trial information.