Adult MDW Dual Cut-Off Accuracy Study

This study will establish the clinical performance of the Monocyte Distribution Width (MDW) parameter on the DxH 900/ DxH 690T hematology analyzers to aid in the detection and risk assessment of patients in the Emergency Department (ED) for progression to sepsis.

Inclusion Criteria: * Adults (18 to 89 years) of all races and ethnicities presenting to the ED * Whole Blood venous samples collected in K2EDTA while the patient was in the ED * First CBC w/diff test ordered within 12 hours of presentation to ED as part of their standard medical care * CBC w/diff tested within 2 hours of specimen collection * Subjects with at least ≥12 hours of follow-up in the ED (or inpatient, if admitted) from presentation Exclusion Criteria: * CBC w/diff test ordered after 12 hours of presentation to ED * Subjects previously enrolled in this study (i.e. subjects may not be enrolled more than once in this study) * Subjects discharged from ED \