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Completed
NCT06894680
Integrating Depression Care Into HIV Services for Older People With HIV Using a Stepped Care, Task-Sharing Approach.
Conditions: Older Adults (50-90 Years), Depression
Sex: All
Ages: 50 Years – 100 Years
Healthy volunteers: No
Phase: NA
Enrollment: 100
Sponsor: Royal Society of Tropical Medicine and Hygiene
Location: Institute of Infectious Diseases Ibadan Oyo State
Summary
Depression levels will be compared using PHQ-9 in the Treatment as Usual arm(TAU) VS intervention arm to see if the stepped care intervention is effective in treating depression. The main questions it aims to answer are:
* Needs assessment of stepped-care integration versus usual care for treating depression in older adults living with HIV?
* How effective will the stepped care task-sharing (SCT) model in reducing depressive symptoms and improving HIV treatment outcomes in older PLHIV in Nigeria? Participants who screen positive for depression PHQ-9 ≥10 will be randomized into 2 arms for treatment using a systemized ballot system: TAU arm and Intervention arm.
TAU arm will receive current treatment available for depression at the HIV center.
Intervention arm will receive the stepped-care intervention in stages based on their symptom severity.
Follow-up assessments at (6 weeks, 3months, 6 months, 9 months and 12 months) will be conducted by assessors who would be blinded to the different groups (TAU arm VS intervention arm).
Eligibility Criteria
Inclusion Criteria:
* Consenting individuals living with HIV
* People living with HIV who are 50 years and above (PLHIV aged ≥50 years)
* Those with a score of ≥10 on the 9-item patient-health questionnaire (PHQ-9).
Exclusion Criteria:
* • Older PLHIV will be assessed for the imminent risk of suicide and if there is an high risk, participant will be excluded.
* Older PLHIV with severe cognitive impairment or diagnosed dementia that limits their ability to provide informed consent or complete study visits will be excluded.
* Participants with comorbidities that can preclude the use of sertraline should be excluded.
Source: ClinicalTrials.gov (NCT06894680). StuddyBuddy aggregates publicly available trial information.