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Active Not Recruiting
NCT06906029
Abdominal aBscess Catheter Sclerotherapy (ABCS)
Conditions: Abdominal Abscess
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE1, PHASE2
Enrollment: 60
Sponsor: University of Alabama at Birmingham
Location: University of Alabama at Birmingham Birmingham Alabama
Summary
This is a single center, two arm phase I/II clinical trial exploring the use of chemical sclerosants (ethanol and povidone iodine) in decreasing the time needed for catheter drainage for patients with non-fistulous intraabdominal abscesses. The target study sample size is 60 patients, 30 in each arm and abscess size is to be a minimum of 3cm in all 3 dimensions. The primary outcomes of interest will be tolerability and need for catheter reinsertion by one week post intervention.
Eligibility Criteria
Inclusion Criteria:
* Male or female, aged over 18years
* Cross-sectional imaging (CT, US, MRI) showing an intraabdominal abscess measuring at last 3cm in each dimension without fistula to the bowel or skin.
* Provision of signed and dated informed consent form
* Stated willingness to comply with all study procedures and availability for the duration of the study
Exclusion Criteria:
* Pregnancy or lactation
* Known allergic reactions to povidone iodine or ethanol
* Hemodynamic instability
Source: ClinicalTrials.gov (NCT06906029). StuddyBuddy aggregates publicly available trial information.