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Completed
NCT06912230
Hypoxia, Appetite, and Energy Intake in Young Female Adults
Conditions: Hypoxia, Altitude, Appetite, Energy Intake
Sex: Female
Ages: 18 Years – 30 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 12
Sponsor: University of Ottawa
Location: Behavioural and Metabolic Research Unit, School of Human Kinetics, Faculty of Health Sciences, University of Ottawa Ottawa Ontario
Summary
The goal of this clinical trial is to investigate the effects of acute passive continuous hypoxemia (simulated high-altitude at rest) on appetite and energy intake in healthy young female adults. The main questions it aims to answer are:
* Does six hours of simulated high-altitude (5000 meters) reduce scores of subjective appetite and energy intake?
* Do changes in appetite and energy intake persist in the hours following the end of hypoxic exposure? Researchers will compare the effects of simulated high-altitude to a control normoxia (sea-level) condition to see if exposure to low oxygen levels independently affect appetite and energy intake.
Participants will:
* Visit the laboratory for a preliminary screening session to assess eligibility.
* Undergo two randomized, single-blind, experimental sessions consisting of six hours of passive exposure to normoxia or hypoxia in a climate-controlled chamber.
* Consume foods provided from a curated list, served in ad libitum quantities, after leaving the laboratory to assess post-exposure energy intake.
Eligibility Criteria
Inclusion Criteria:
* English or French speaking
* Ability to provide informed consent
Exclusion Criteria:
* History or evidence of chronic disease
* Current use of hypolipemic medication
* Current use of hormonal contraceptives
* Current use of antidepressants
* Current use of anticoagulants
* Ongoing smoking status
* Experiencing pregnancy, puerperium, or irregular menstrual cycles
Source: ClinicalTrials.gov (NCT06912230). StuddyBuddy aggregates publicly available trial information.