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Completed
NCT06921525
Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye
Conditions: Dry Eye
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Phase: PHASE1, PHASE2
Enrollment: 50
Sponsor: Ehab Mohamed Elsayed Mohamed Saad
Location: Ebsar Eye Center Banhā Benha
Summary
This study aims to compare the effects of azithromycin and tea tree oil on the clinical outcomes and inflammatory profile of patients with MGD-associated DED. By focusing on changes in tear IL-8 and IL-17 levels, the study seeks to provide insights into the differential mechanisms of these two treatments and their potential in addressing inflammation-driven DED.
Eligibility Criteria
Inclusion Criteria:
* Tear Break-Up Time (TBUT) ≤10 seconds.
* Ocular Surface Disease Index (OSDI) score ≥20.
* Willingness to comply with study requirements and provide informed consent.
Exclusion Criteria:
* History of ocular surgery or trauma within the past 6 months.
* Use of systemic or topical anti-inflammatory medications within 4 weeks prior to enrollment.
* Known hypersensitivity to azithromycin or tea tree oil.
* Presence of other ocular surface diseases unrelated to MGD.
Source: ClinicalTrials.gov (NCT06921525). StuddyBuddy aggregates publicly available trial information.
