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Enrolling By Invitation
NCT06926322
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Conditions: Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
Sex: All
Ages: 4 Years – 8 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 108
Sponsor: Ain Shams University
Location: Faculty of dentistry Ain shams university Cairo
Summary
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment. A simple and effective technique such as Lesion Sterilization and Tissue Repair offers a solution to cases with poor prognosis; however, the medicaments used in this technique have some limitations. This study will evaluate three different medicaments regarding the clinical success, radiographic success, and antibacterial activity.
Eligibility Criteria
Inclusion Criteria:
* Healthy cooperative children of both sexes in the age range of 4-8 years old.
* Children with consenting parents who accept to participate in the study and sign the consent forms.
* Children with mandibular primary molars with clinical and radiographic signs of pulpal necrosis.
Exclusion Criteria:
* Children with hypersensitivity to any of the used medicaments.
* Non-restorable teeth without sufficient coronal structure for placement of rubber dam isolation and restoration with stainless steel crowns
* Non-restorable teeth with perforated pulpal floor
Source: ClinicalTrials.gov (NCT06926322). StuddyBuddy aggregates publicly available trial information.