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NCT06932640
Continuous Assessment of Brain Blood Perfusion in Subarachnoid Hemorrhage Patients Using Near-Infrared Spectroscopy (NIRS)
Conditions: Subarachnoid Hemorrhage, Aneurysmal
Sex: All
Ages: 18 Years – 89 Years
Healthy volunteers: No
Enrollment: 120
Sponsor: University of Alabama at Birmingham
Location: The University of Alabama at Birmingham Birmingham Alabama
Summary
The goal of this observational study is to continuously assess cerebral autoregulation in patients with subarachnoid hemorrhage (SAH) using cerebral oximetry index (COx) and hemoglobin volume reactivity index (HVx). The main question it aims to answer is: Whether optimal perfusion pressure is dynamic and changes with time in patients with SAH, and that autoregulation is disrupted in patients during the course of SAH, contributing to delayed cerebral ischemia (DCI).
Eligibility Criteria
Inclusion Criteria:
* Patients aged 18 to 89 years who are admitted to the Neurological Intensive Care Unit (Neuro ICU) between March 2025 and December 2026 for aneurysmal subarachnoid hemorrhage (SAH).
Exclusion Criteria:
* Patients under 18 years old
* Prisoners
* Pregnant women
* Patients enrolled in concurrent ongoing interventional trial
* Students of UAB
* Employees of UAB
* Patients who undergoes frontal decompression surgery resulting bone flap deficit where NIRS monitoring pads could not be applied.
Source: ClinicalTrials.gov (NCT06932640). StuddyBuddy aggregates publicly available trial information.
