Acute Effects of THC in Older Adult

Sex: All

Ages: 21 Years – N/A

Healthy volunteers: Yes

Phase: PHASE1

Enrollment: 60

Sponsor: Yale University

Summary

The primary objective of this study is to determine if increasing age confers greater vulnerability to the acute A) cognitive (e.g., memory, attention, psychomotor function), B) subjective (e.g., anxiogenic and rewarding effects), and C) cardiovascular (heart rate and blood pressure), effects of THC in adults \> 21 years old. The secondary aims of the study are to explore age-related acute effects of THC on electrophysiological indices of information processing (e.g., auditory steady-state response (ASSR), oddball paradigm \[P300\], and resting state cortical noise) and to determine age-related differences in the metabolism of THC.

Eligibility Criteria

* Ability to provide informed consent * No history (current or past) of unstable or serious medical, neurological or psychiatric conditions. * High school education or greater * No positive pregnancy test and/or lactation/ planning to nurse while in this study * English speaking

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06948136). StuddyBuddy aggregates publicly available trial information.