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NCT06965335
Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study
Conditions: Colo-rectal Cancer
Sex: All
Ages: 18 Years – 40 Years
Healthy volunteers: No
Enrollment: 20
Sponsor: Niguarda Hospital
Location: ASST Grande Ospedale Metropolitano Niguarda Milan
Summary
Observational, retrospective and prospective multicentric Italian study of patients diagnosed with colorectal cancer between age 18-40, aiming at underpinning the biology of vEO-CRC, including colibactin as well as a broader proteo-genomic characterization, to identify potential new therapeutic targets specifically directed to this peculiar subset of patients.
Eligibility Criteria
1. Patients with diagnosis of colorectal cancer (vEO-CRC: 18-40 years of age), or SO-CRC diagnosed later than age 60;
2. Informed consent signature from alivepatient;
3. Availability of formalin-fixed paraffin embedded (FFPE) tumor samples (5 FFPE 4uM thick slides and 10 FFPE 10 uM thick slides) and/or fresh tumor tissue retrieved from a biopsy or surgical procedure performed as per clinical standard of care.
Source: ClinicalTrials.gov (NCT06965335). StuddyBuddy aggregates publicly available trial information.
