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Active Not Recruiting
NCT06972069
Tolerance Through Mixed Chimerism (Sip-Tego)
Conditions: Kidney Failure, Transplant Recipient (Kidney), Transplant Tolerance, Immunosuppresion, Immunosuppression After Kidney Transplantation
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Phase: EARLY_PHASE1
Enrollment: 12
Sponsor: Tatsuo Kawai, MD, PhD
Location: Massachusetts General Hospital Boston Massachusetts
Summary
This is an open-label, single-institution study to assess the safety and the efficacy of the Sip-Tego regimen for the induction of donor-specific immunologic unresponsiveness to a renal allograft. The investigators propose to treat 6 adult subjects in end-stage renal disease (ESRD) who do not demonstrate evidence of prior sensitization.
Eligibility Criteria
Recipient Inclusion Criteria:
1. Male or female 18-65 years of age.
2. Subjects with chronic kidney disease stage V (GFR\
Source: ClinicalTrials.gov (NCT06972069). StuddyBuddy aggregates publicly available trial information.
