Assessment of Drug Liking In Peri-procedural Clinical Settings

The purpose of this study is to evaluate whether medications used in peri-procedural clinical settings can modulate drug liking.

Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status classification of I, II or III * Candidates who are expected to receive fentanyl up to 3 mcg/kg IBW for their scheduled for surgery or procedure Exclusion Criteria: * Craniofacial abnormalities * Known or suspected difficult intubation or mask ventilation * Known or suspected need for rapid sequence induction and intubation * Allergies or hypersensitivities to droperidol or fentanyl * Clinically significant pulmonary disease, such as chronic obstructive lung disease requiring long-term oxygen therapy, or other conditions that, in the study team's judgment, may increase the risk of severe respiratory depression with opioid administration * History of long QT syndrome * History of Torsades de Pointes * History of psychosis * History of movement disorders e.g. Parkinson's Disease * Past chronic use of anti-psychotics * Current use of droperidol, levodopa, lithium, clozapine, metoclopramide, benzodiazepines * Current use of opioids * History of opiate abuse within the last 3 years * Known or suspected severe chronic pain condition that require use of opiates or limit daily activities * History of pheochromocytoma * History of concomitant prolactin-dependent tumors e.g. prolactinoma, breast cancer * Pregnancy or nursing * Current use of antiemetic medication (i.e., 5HT or dopamine antagonists) * Active seizure disorder * Active mental health disorders resulting in functional impairment * Current use of psychostimulant medications (Adderall) * Current use of CNS depressants (e.g., barbiturates, benzodiazepines) * Severe renal insufficiency (Stage 4 or 5) * Impaired cognitive function * Regular Cannabis use (2+ times per week) * Current history of substance abuse disorder. * Failure to satisfy the investigator of fitness to participate for any other reason