← Back to all trials
Enrolling By Invitation
NCT07023757
Effect of Age on PRF Quality; Assessed by Evaluating Healing Outcomes of ARP
Conditions: Healing Wound
Sex: All
Ages: 20 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 44
Sponsor: University of Michigan
Location: University of Michigan School of Dentistry Ann Arbor Michigan
Summary
This study will examine whether using PRF and your age are going to affect the healing and regeneration benefits gained from PRF.
Eligibility Criteria
Inclusion Criteria:
1. Age range: 20 to 80 years.
2. Patients must require tooth extraction (molars) as a result of caries, periodontal disease, tooth fracture or deemed unrestorable.
3. Non-infected sockets with intact buccal bone (≥1.5 mm in thickness measured through calipers)
4. Patients interested in implant placement following tooth extraction.
Exclusion Criteria:
1. Allergies or hypersensitivities to study related medications.
2. Hematologic disorders/blood dyscrasias.
3. Active infectious diseases of any kind.
4. Liver or kidney dysfunction/failure.
5. Uncontrolled diabetes (HbA1c \> 8).
6. Active cancer treatment - such as active chemotherapy or radiation therapy.
7. Taking medications that will affect their bone healing (for example, bisphosphonates, Long-term NSAIDs use, Steroid).
8. Metabolic bone diseases that affect bone healing such as osteoporosis.
9. Pregnant or lactating women (self-reported).
10. Smoke 10 or more cigarettes per day (self-reported).
11. Poor oral hygiene.
12. Systemic diseases that compromise the immune system
13. Anti-coagulant therapy
Source: ClinicalTrials.gov (NCT07023757). StuddyBuddy aggregates publicly available trial information.