Gynecological Impact of Allogeneic Hematopoietic Stem Cell Transplantation in Adults

Gynecological impact and infertility are major issues for women after allogeneic hematopoietic stem cell transplantation. The aim of the present study is to investigate the prevalence of gynecological complications after allogeneic hematopoietic stem cell transplantation for acute leukemia in adulthood. By conducting a single-center retrospective descriptive analysis, the prevalence, follow-up and treatment of gynecological complications -including premature ovarian failure, vulvovaginal graft-versus-host-disease, cervical pathology- will be analysed

Inclusion Criteria: * Women diagnosed with acute leukemia, who underwent allogeneic hematopoietic stem cell transplantation in adulthood (\>18 years), * Aged 20 to 45 at the time of evaluation, * At least 2 years post-transplant. * French-speaking patients, without comprehension disorders, and literate, * No objection to participation. Exclusion Criteria: * Premature ovarian failure prior to management of haemopathy, post-transplant relapse, * Patient under legal protection