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Completed
NCT07053774
Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain
Conditions: Pain, Acute
Sex: All
Ages: 18 Years – 75 Years
Healthy volunteers: Yes
Phase: PHASE2
Enrollment: 24
Sponsor: Wake Forest University Health Sciences
Location: Atrium Health Wake Forest Baptist Winston-Salem North Carolina
Summary
The goal of this research study is to find out how well oxytocin works to reduce pain. Oxytocin will be given intravenously (IV) and as a nasal spray. The study team also hopes to find out if the participants age, weight, or sex effects how well the study drug works.
Participants will be exposed to a heater on the skin at a training visit and rate how much pain different temperatures cause. On two separate visits, participants will use a nasal spray and get an IV infusion. After the IV and nasal spray, participants will rate the pain of the same skin heating temperature at various time points for 4 hours.
Eligibility Criteria
Inclusion Criteria:
* Male or female \> 18 and ≤75 years of age, Body Mass Index (BMI) \
Source: ClinicalTrials.gov (NCT07053774). StuddyBuddy aggregates publicly available trial information.