← Back to all trials
Recruiting
NCT07072195
A Study of AMC6156 in People With Sarcopenia
Conditions: Sarcopenia in Elderly, Sarcopenia
Sex: All
Ages: 65 Years – N/A
Healthy volunteers: No
Phase: PHASE2
Enrollment: 80
Sponsor: Animuscure Inc.
Location: CHA Bundang Medical Center Seongnam-si Gyeonggi-do
Summary
This clinical trial aims to find out whether AMC6156 can improve physical function and is safe in older adults with sarcopenia. Participants will take AMC6156 or a placebo daily for 12 weeks, and their movement, strength, and safety will be regularly monitored through tests and checkups.
Eligibility Criteria
Inclusion Criteria:
* Voluntary participation with written informed consent
* Male ≥ 65 years or postmenopausal female
* Diagnosed with sarcopenia:
* ASM \< 7.0 kg/m² (men) or \< 5.4 kg/m² (women)
* Plus low handgrip strength or SPPB ≤ 9
* MNA screening score ≥ 8
* Body weight ≥ 35 kg, BMI between 15-30 kg/m²
* Willing and able to follow exercise and nutrition guidance
Exclusion Criteria:
* Allergy to investigational drug
* History of GI bleeding, ulcers, or severe liver/kidney/heart disease
* QTc ≥ 450 ms with symptoms
* Severe COPD, uncontrolled diabetes or thyroid disease
* Diseases causing cachexia or muscle wasting (e.g., ALS, Parkinson's)
* Vitamin D deficiency (\
Source: ClinicalTrials.gov (NCT07072195). StuddyBuddy aggregates publicly available trial information.
