A Study of LY3549492 in Healthy Weight Adult Participants

The main purpose of this study is to evaluate the safety and tolerability of LY3549492 in adult participants with a healthy body max index (BMI) of 22 to 25 kilograms per square meter (kg/m2). Participation in the study will last about 13 months.

Inclusion Criteria: * Have a body mass index (BMI) within the range of 22 to 25 kilograms per square meter (kg/m2) * Have had a stable body weight for 3 months prior to screening Exclusion Criteria: * Have type 1 diabetes, latent autoimmune diabetes in adults, or a history of ketoacidosis or hyperosmolar coma * Have: * type 2 diabetes and on antidiabetic therapy (except type 2 diabetes being managed with diet and/or stable dose of metformin) * rare forms of diabetes mellitus, or * hemoglobin A1c (HbA1c) \>8% * Have poorly controlled hypertension * Have any of the following cardiovascular conditions within 12 months prior to screening: * acute myocardial infarction * stroke * unstable angina, or * hospitalization due to congestive heart failure. * Have a history of New York Heart Association Functional Classification III or IV congestive heart failure * Have signs and symptoms of liver disease * Have a history of pancreatitis * Have taken medications or alternative remedies for weight loss or weight gain within 3 months prior to screening