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Recruiting
NCT07099443
Determinants of the Response to BTK Degraders (BTKd) in Chronic Lymphocytic Leukemia
Conditions: Chronic Lymphocytic Leukemia, BTK Degraders
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 60
Sponsor: Nantes University Hospital
Location: CHU de Angers Angers
Summary
The aim of the REBELLE cohort - bio-collection is to collect samples from patients with Chronic Lymphocytic Leukemia candidates or those exposed to BTK degraders to evaluate the mechanisms of resistance to these new molecules. To do this, an additional blood or bone marrow sample to those planned in the context of patient care or a residual lymph node biopsy sample will be collected after signing consent.
Eligibility Criteria
Inclusion Criteria:
* Patient with CLL candidates ou exposed to BTKd
* Patient who has provided informed consent to participate in the study.
* Patient covered by a social security health insurance plan
Exclusion Criteria:
* Minor patients.
* Adults under guardianship.
* Protected persons.
Source: ClinicalTrials.gov (NCT07099443). StuddyBuddy aggregates publicly available trial information.
